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Chemical. CAS 16846-24-5. Formula C42H69NO15. MW 827.99. Synthetic. A member of the leucomycin family of macrolide antibiotics produced by Streptomyces kitasatoensis. May overcome anticancer drug resistance by inhibiting the binding of vinblastine or cyclosporin A to P-glycoprotein Pgp. An antimicrobial against a wide variety of pathogens.
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Thioisonicotinamide (4-Pyridylthioamide) is a synthetic intermediate used for pharmaceutical synthesis. This high-purity compound is provided as a solid, suitable for various laboratory applications.
Purity: 99.82%
Appearance: Solid
Color: Light yellow to yellow
Molecular formula: C6H6N2S
Molecular weight: 138.19
Recommended storage for powder: -20°C for 3 years, 4°C for 2 years
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Thioisonicotinamide (Pyridine-4-carbothioamide Isothionicotinamide 4-Pyridylthiocarboxamide) is a synthetic intermediate used for pharmaceutical synthesis
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Sulforaphane (CAS 4478-93-7) is a naturally occurring isothiocyanate abundantly found in vegetables especially broccoli It acts primarily through activation of the Keap1-Nrf2 signaling pathway enhancing cellular defense against oxidative and electrophilic stress Sulforaphane has demonstrated antiproliferative activity in vitro as shown by dose-dependent cell cycle arrest at G2/M and apoptosis induction in HT29 human colon carcinoma cells Such effects involve elevated cyclin A and B1 levels increased pro-apoptotic Bax expression mitochondrial cytochrome c release and poly(ADP-ribose) polymerase cleavage These properties make sulforaphane relevant for investigating cancer chemoprevention and cellular stress responses
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